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Hiroyuki Aburatani Selected Research

Glioma (Gliomas)

3/2024Region-specific DNA hydroxymethylation along the malignant progression of IDH-mutant gliomas.
1/2019Reduced Neoantigen Expression Revealed by Longitudinal Multiomics as a Possible Immune Evasion Mechanism in Glioma.
1/2019DNA demethylation is associated with malignant progression of lower-grade gliomas.
1/2018Identification of a novel fusion gene HMGA2-EGFR in glioblastoma.
12/2017Distinct molecular profile of diffuse cerebellar gliomas.
1/2017Genetic and epigenetic stability of oligodendrogliomas at recurrence.
4/2015Evolution of DNA repair defects during malignant progression of low-grade gliomas after temozolomide treatment.
1/2014Mutational analysis reveals the origin and therapy-driven evolution of recurrent glioma.
1/2014H3F3A K27M mutations in thalamic gliomas from young adult patients.
7/2011Homozygously deleted gene DACH1 regulates tumor-initiating activity of glioma cells.
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Hiroyuki Aburatani Research Topics

Disease

127Neoplasms (Cancer)
04/2024 - 01/2002
26Carcinogenesis
01/2020 - 01/2002
16Hepatocellular Carcinoma (Hepatoma)
10/2019 - 06/2002
13Carcinoma (Carcinomatosis)
01/2023 - 07/2002
12Glioma (Gliomas)
03/2024 - 01/2004
12Stomach Neoplasms (Stomach Cancer)
05/2023 - 01/2002
11Hypoxia (Hypoxemia)
11/2021 - 04/2007
11Neoplasm Metastasis (Metastasis)
01/2021 - 03/2003
9Fibrosis (Cirrhosis)
01/2022 - 12/2003
8Inflammation (Inflammations)
01/2023 - 09/2002
8Colorectal Neoplasms (Colorectal Cancer)
01/2019 - 01/2007
8Breast Neoplasms (Breast Cancer)
01/2018 - 12/2003
8Liver Neoplasms (Liver Cancer)
01/2018 - 06/2006
7Body Weight (Weight, Body)
01/2023 - 09/2002
7Heart Failure
01/2023 - 12/2003
7Lung Neoplasms (Lung Cancer)
01/2022 - 03/2003
7Adenocarcinoma of Lung
10/2020 - 12/2005
7Adenocarcinoma
01/2020 - 10/2005
6Melanoma (Melanoma, Malignant)
01/2021 - 11/2004
6Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
01/2020 - 03/2005
6Glioblastoma (Glioblastoma Multiforme)
01/2019 - 01/2004
6Leiomyosarcoma
10/2016 - 01/2011
6Insulin Resistance
10/2012 - 12/2002
5Prostatic Neoplasms (Prostate Cancer)
02/2018 - 01/2009
5Colonic Neoplasms (Colon Cancer)
10/2014 - 08/2004
4Leukemia
01/2022 - 06/2012
4Pancreatic Neoplasms (Pancreatic Cancer)
01/2020 - 01/2012
4Oligodendroglioma
01/2019 - 06/2002
4Bone Resorption
09/2013 - 06/2004
3Small Cell Lung Carcinoma (Small Cell Lung Cancer)
04/2024 - 01/2020
3Astrocytoma (Pilocytic Astrocytoma)
03/2024 - 01/2004
3Non-alcoholic Fatty Liver Disease
10/2023 - 01/2020
3Sarcoma (Soft Tissue Sarcoma)
01/2023 - 04/2010
3Dilated Cardiomyopathy (Cardiomyopathy, Congestive)
01/2023 - 10/2019
3Renal Cell Carcinoma (Grawitz Tumor)
01/2022 - 10/2007
3Down Syndrome (Down's Syndrome)
01/2021 - 11/2004
3Starvation
10/2019 - 05/2013
3Microsatellite Instability
04/2019 - 02/2012
3Squamous Cell Carcinoma (Epidermoid Carcinoma)
12/2018 - 01/2008
3Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
01/2018 - 11/2012
3Epstein-Barr Virus Infections
08/2017 - 07/2002
3Germ Cell and Embryonal Neoplasms (Germ Cell Tumor)
02/2014 - 09/2006

Drug/Important Bio-Agent (IBA)

38Proteins (Proteins, Gene)FDA Link
10/2018 - 02/2003
33DNA (Deoxyribonucleic Acid)IBA
03/2024 - 01/2003
26RNA (Ribonucleic Acid)IBA
03/2024 - 12/2003
16Biomarkers (Surrogate Marker)IBA
05/2023 - 04/2004
14OligonucleotidesIBA
12/2007 - 01/2002
13Messenger RNA (mRNA)IBA
01/2021 - 07/2002
13Transcription Factors (Transcription Factor)IBA
01/2021 - 02/2006
10Histones (Histone)IBA
01/2023 - 01/2009
9AntigensIBA
12/2018 - 03/2005
9ChromatinIBA
01/2018 - 02/2007
9GlypicansIBA
06/2009 - 02/2003
8Transforming Growth Factors (Transforming Growth Factor)IBA
01/2022 - 03/2009
8Monoclonal AntibodiesIBA
04/2015 - 12/2005
7Glucose (Dextrose)FDA LinkGeneric
01/2023 - 12/2002
7Phosphotransferases (Kinase)IBA
01/2023 - 10/2007
7Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
03/2020 - 11/2004
7ErbB Receptors (EGF Receptor)IBA
01/2020 - 04/2007
6Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
01/2020 - 01/2002
6Androgen Receptors (Androgen Receptor)IBA
02/2018 - 01/2009
6AndrogensIBA
02/2018 - 01/2009
6Small Interfering RNA (siRNA)IBA
04/2017 - 04/2010
6LigandsIBA
11/2016 - 09/2002
6MucinsIBA
04/2015 - 05/2005
6Transforming Growth Factor beta (TGF-beta)IBA
04/2009 - 12/2002
5Insulin (Novolin)FDA Link
10/2023 - 12/2002
5CytokinesIBA
01/2023 - 07/2002
5Long Noncoding RNAIBA
01/2021 - 06/2013
5AntibodiesIBA
12/2018 - 04/2006
5Cadherins (E-Cadherin)IBA
09/2016 - 01/2002
4Immune Checkpoint InhibitorsIBA
04/2024 - 01/2020
4Triglycerides (Triacylglycerol)IBA
01/2020 - 02/2002
4Complementary DNA (cDNA)IBA
01/2012 - 03/2005
4alpha-Fetoproteins (alpha-Fetoprotein)IBA
04/2009 - 04/2004
3hydrogen sulfite (bisulfite)IBA
03/2024 - 01/2007
3ParaffinIBA
03/2024 - 04/2019
3VimentinIBA
01/2022 - 11/2010
3Peptide Hydrolases (Proteases)FDA Link
01/2022 - 08/2004
3(R)-2-(3-((benzoxazol-2-yl-d4 (3- (4- methoxyphenoxy- d7)propyl)amino)methyl)phenoxy) butanoic acidIBA
01/2022 - 01/2020
3Telomerase (Telomerase Reverse Transcriptase)IBA
01/2021 - 08/2006
3CalcineurinIBA
01/2021 - 11/2004
3Untranslated RNA (Noncoding RNA)IBA
01/2021 - 01/2016
3Transforming Growth Factor-beta Type II ReceptorIBA
01/2020 - 04/2009
3NucleotidesIBA
04/2019 - 01/2011
3EpitopesIBA
12/2018 - 12/2005
3Protein Isoforms (Isoforms)IBA
01/2016 - 12/2006
3DecitabineFDA Link
01/2016 - 01/2010
3Hormones (Hormone)IBA
07/2014 - 01/2009
3TOR Serine-Threonine KinasesIBA
01/2014 - 01/2012
3CohesinsIBA
10/2013 - 02/2008
3Hypoxia-Inducible Factor 1IBA
06/2013 - 03/2009
3NF-kappa B (NF-kB)IBA
11/2012 - 06/2004
3Indicators and Reagents (Reagents)IBA
11/2010 - 12/2005
3beta CateninIBA
06/2010 - 02/2006

Therapy/Procedure

32Therapeutics
01/2023 - 03/2005
7Immunotherapy
01/2022 - 03/2005
5Drug Therapy (Chemotherapy)
01/2017 - 06/2002
3Transplantation
11/2012 - 11/2010
3Lasers (Laser)
10/2012 - 01/2010